Publications

Direct Expression of CPT1a Enables a High Throughput Platform for the Discovery of CPT1a Modulators

Chen, Jason; Tran, Tuyen; Wong, Anthony; Wang, Luofei; Annaluru, Pranavi; Sreekanth, Vibha; Murthy, Samika; Munjeti, Laasya; Park, Tanya; Bhat, Utkarsh; Leong, Glynnis; Li, Yumeng; Chen, Simeng; Kong, Natalie; Raval, Rushika; Xie, Yining; Somani, Shreya; Bhambhani; Aditi; Zhu, Zoey; Chu, Landen; Dosch, Kimai; Njoo, Edward; Chen, Zhan. BioRXiv Preprint 2024, in review. DOI: https://www.preprints.org/manuscript/202412.1288/v1

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Evaluation of machine learning models for the accelerated prediction of Density Functional Theory calculated 19F chemical shifts based on local atomic environments

Li, Sophia; Wang, Emma; Pei, Leia; Deb, Sourodeep; Panda, Raina; Prabhala, Prashanth; Eltepu, Shiven; Akl, Marx; McMahan, Larry; Njoo, E.S. Artificial Intelligence Chemistry 2024, in press. DOI: https://doi.org/10.1016/j.aichem.2024.100078

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Benchtop 19F NMR Spectroscopy optimized Knorr pyrazole synthesis of Celecoxib and Mavacoxib, 3-(trifluoromethyl) pyrazolyl benzenesulfonamides Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

Chyu, Andrew; Xi, Selina; Kim, Joshua; Liu, Galen; Chan, Indalina; Hong, Seoyeon; Ke, Allen; Lavery, Thomas; Marimuthu, Anushree; Akula, Arjun; Njoo, E.S. Spectroscopy J 2024, 2(4), 206-215. DOI: https://doi.org/10.3390/spectroscj2040014

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Synthesis and Evaluation of Carmofur Analogs as Antiproliferative Agents, Inhibitors to the Main Protease (Mpro) of SARS-CoV-2, and Membrane Rupture-Inducing Agents

Gu, Tiffany; Lu, Amber; Wang, Xina; Brahan, Natalie; Xu, Lexi; Zhang, Leyuan; Su, Kaitlyn; Seow, Kody; Vu, Julia; Luk, Charissa; Lee, Jade; Raman, Anirudh; Pazzi, Joseph; Njoo, E.S. BioRXiv 2024. DOI: https://doi.org/10.1101/2024.10.11.617727 

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Synthesis, antiproliferative activity, and biological profiling of C-19 trityl and silyl ether andrographolide analogs in colon cancer and breast cancer cells

Gu, Tiffany; Raval, Rushika; Bashkin, Zachary; Zhou, Carina; Ko, Sanghyuk; Kong, Natalie; Hong, Seoyeon; Bhaskara, Aditya; Shah, Samarth; Joshi, Aditi; Thellakal, Samahith; Rim, Kaitlyn; Marimuthu, Anushree; Venkatesan, Srishti; Wang, Emma; Li, Sophia; Jayabalan, Aditi; Tao, Alice; Fang, Yilin, Xia, Lorelei; Chui, Aidan; Shu, Emily; Zhang, Tracy; Chen, Zhan; Njoo, Edward. Bioorg. Medicinal Chemistry Letters 2024, manuscript accepted. [ChemRXiv Preprint] DOI: 10.26434/chemrxiv-2024-lrkln

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C-4 analogs of podophyllotoxin as tubulin inhibitors: Synthesis, biological evaluation, and structure-activity relationship

Lu, Breanna; Xu, Lexi; Chen, Harriet; Yu, Grace; Khow, Kimberly; Yang, Stella; Dinker, Arushi; Njoo, E.S. Natural Product Research 2024, 1, 1-7. DOI: https://doi.org/10.1080/14786419.2024.2410410 

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Mechanistic Deconvolution of Autoreduction in Tetrazolium-based Cell Viability Assays

Tran, Kara; Shah, Aashi; Saha, Rittika; Song, Claire; Liang, Emily; Njoo, E.S. Journal of Emerging Investigators 2024, online. DOI: https://doi.org/10.59720/22-186

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